• Hazard identification of nanomaterials: In silico unraveling of descriptors for cytotoxicity and genotoxicity 

      El Yamani, Naouale; Mariussen, Espen; Gromelski, Maciej; Wyrzykowska, Ewelina; Grabarek, Dawid; Puzyn, Tomasz; Tanasescu, Speranta; Dusinska, Maria; Rundén-Pran, Elise (Peer reviewed; Journal article, 2022)
      Hazard identification and safety assessment of the huge variety of nanomaterials (NMs), calls for robust and validated toxicity screening tests in combination with cheminformatics approaches to identify factors that can ...
    • Linking Nanomaterial-Induced Mitochondrial Dysfunction to Existing Adverse Outcome Pathways for Chemicals 

      Murugadoss, Sivakumar; Vrček, Ivana Vinković; Schaffert, Alexandra; Paparella, Martin; Pem, Barbara; Sosnowska, Anita; Stępnik, Maciej; Martens, Marvin; Willighagen, Egon L.; Puzyn, Tomasz; Cimpan, Mihaela-Roxana; Lemaire, Frauke; Mertens, Birgit; Dusinska, Maria; Fessard, Valérie; Hoet, Peter H. (Peer reviewed; Journal article, 2023)
      The Adverse Outcome Pathway (AOP) framework plays a crucial role in the paradigm shift of toxicity testing towards the development and use of new approach methodologies. AOPs developed for chemicals are in theory applicable ...
    • NanoSolveIT Project: Driving nanoinformatics research to develop innovative and integrated tools for in silico nanosafety assessment 

      Afantitis, Antreas; Melagraki, Georgia; Isigonis, Panagiotis; Tsoumanis, Andreas; Varsou, Dimitra Danai; Valsami-Jones, Eugenia; Papadiamantis, Anastasios; Ellis, Laura-Jayne; Sarimveis, Haralambos; Doganis, Philip; Karatzas, Pantelis; Tsiros, Periklis; Liampa, Irene; Lobaskin, Vladimir; Greco, Dario; Serra, Angela; Kinaret, Pia Anneli Sofia; Saarimaki, Laura Aliisa; Grafström, Roland; Kohonen, Pekka; Nymark, Penny; Willighagen, Egon; Puzyn, Tomasz; Rybinska-Fryca, Anna; Lyubartsev, Alexander; Jensen, Keld Alstrup; Brandenburg, Gerit; Lofts, Stephen; Svendsen, Claus; Harrison, Samuel; Maier, Dieter; Tamm, Kaido; Janes, Jaak; Sikk, Lauri; Dusinska, Maria; Longhin, Eleonora Marte; Rundén-Pran, Elise; Mariussen, Espen; El Yamani, Naouale; Unger, Wolfgang; Radnik, Jörg; Tropsha, Alexander; Cohen, Yoram; Leszcynski, Jerzy; Hendren, Christine Ogilvie; Wiesner, Mark; Winkler, David; Suzuki, Noriyuki; Yoon, Tae Hyun; Choi, Jang-Sik; Gulumian, Mary; Lynch, Iseult (Peer reviewed; Journal article, 2020)
      Nanotechnology has enabled the discovery of a multitude of novel materials exhibiting unique physicochemical (PChem) properties compared to their bulk analogues. These properties have led to a rapidly increasing range of ...
    • A strategy towards the generation of testable adverse outcome pathways for nanomaterials 

      Murugadoss, Sivakumar; Vrcek, Ivana Vinkovic; Pem, Barbara; Jagiello, Karolina; Judzinska, Beata; Sosnowska, Anita; Martens, Marvin; Willighagen, Egon L.; Puzyn, Tomasz; Dusinska, Maria; Cimpan, Mihaela-Roxana; Fessard, Valérie; Hoet, Peter H. (Peer reviewed; Journal article, 2021)
      Manufactured nanomaterials (NMs) are increasingly used in a wide range of industrial applications leading to a constant increase in the market size of nano-enabled products. The increased production and use of NMs are ...